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Everything in moderation: Proteolytic regulation of centrosome duplication

The presence of too many or too few centrosomes at mitosis can disrupt the timely formation of a bipolar spindle and may lead to aneuploidy and cancer. Strict control of centrosome duplication is therefore crucial. Centrosome duplication must occur once per cell cycle and the number of new centriole...

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Detalles Bibliográficos
Autor principal: Peel, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704442/
https://www.ncbi.nlm.nih.gov/pubmed/24058868
http://dx.doi.org/10.4161/worm.22497