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Everything in moderation: Proteolytic regulation of centrosome duplication
The presence of too many or too few centrosomes at mitosis can disrupt the timely formation of a bipolar spindle and may lead to aneuploidy and cancer. Strict control of centrosome duplication is therefore crucial. Centrosome duplication must occur once per cell cycle and the number of new centriole...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Landes Bioscience
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704442/ https://www.ncbi.nlm.nih.gov/pubmed/24058868 http://dx.doi.org/10.4161/worm.22497 |