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A Reporter Screen in a Human Haploid Cell Line Identifies CYLD as a Constitutive Inhibitor of NF-κB

The development of forward genetic screens in human haploid cells has the potential to transform our understanding of the genetic basis of cellular processes unique to man. So far, this approach has been limited mostly to the identification of genes that mediate cell death in response to a lethal ag...

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Detalles Bibliográficos
Autores principales: Lee, Clarissa C., Carette, Jan E., Brummelkamp, Thijn R., Ploegh, Hidde L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704534/
https://www.ncbi.nlm.nih.gov/pubmed/23861985
http://dx.doi.org/10.1371/journal.pone.0070339