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A Reporter Screen in a Human Haploid Cell Line Identifies CYLD as a Constitutive Inhibitor of NF-κB
The development of forward genetic screens in human haploid cells has the potential to transform our understanding of the genetic basis of cellular processes unique to man. So far, this approach has been limited mostly to the identification of genes that mediate cell death in response to a lethal ag...
Autores principales: | Lee, Clarissa C., Carette, Jan E., Brummelkamp, Thijn R., Ploegh, Hidde L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704534/ https://www.ncbi.nlm.nih.gov/pubmed/23861985 http://dx.doi.org/10.1371/journal.pone.0070339 |
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