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Clinical significance of the thymidylate synthase, dihydropyrimidine dehydrogenase, and thymidine phosphorylase mRNA expressions in hepatocellular carcinoma patients receiving 5-fluorouracil-based transarterial chemoembolization treatment

PURPOSE: To determine whether 5-fluorouracil (5-FU) sensitivity is associated with the mRNA expressions of thymidylate synthase (TS), dihydropyrimidine dehydrogenase (DPD), and thymidine phosphorylase (TP) in patients with hepatocellular carcinoma (HCC) treated with 5-FU-based transarterial chemoemb...

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Detalles Bibliográficos
Autores principales: Zhao, Hongyun, Zhao, Yuanyuan, Guo, Ying, Huang, Yan, Lin, Suxia, Xue, Cong, Xu, Fei, Zhang, Yang, Zhao, Liping, Hu, Zhihuang, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704606/
https://www.ncbi.nlm.nih.gov/pubmed/23861589
http://dx.doi.org/10.2147/OTT.S46498