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Reactivation of immune responses against Mycobacterium tuberculosis by boosting with the CpG oligomer in aged mice primarily vaccinated with Mycobacterium bovis BCG

BACKGROUND: Mycobacterium bovis bacillus Calmette Guérin (BCG) vaccine, which has been inoculated to more than one billion people world-wide, has significant effect in preventing tuberculous meningitis and miliary tuberculosis (TB) in neonate and early childhood. However, BCG fails to adequately pro...

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Detalles Bibliográficos
Autores principales: Taniguchi, Keiichi, Takii, Takemasa, Yamamoto, Saburo, Maeyama, Jun-ichi, Iho, Sumiko, Maruyama, Mitsuo, Iizuka, Narushi, Ozeki, Yuriko, Matsumoto, Sohkichi, Hasegawa, Tomohiro, Miyatake, Yuuji, Itoh, Saotomo, Onozaki, Kikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704610/
https://www.ncbi.nlm.nih.gov/pubmed/23799936
http://dx.doi.org/10.1186/1742-4933-10-25