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Human Ubc9 Is Involved in Intracellular HIV-1 Env Stability after Trafficking out of the Trans-Golgi Network in a Gag Dependent Manner

The cellular E2 Sumo conjugase, Ubc9 interacts with HIV-1 Gag, and is important for the assembly of infectious HIV-1 virions. In the previous study we demonstrated that in the absence of Ubc9, a defect in virion assembly was associated with decreased levels of mature intracellular Envelope (Env) tha...

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Detalles Bibliográficos
Autores principales: Bohl, Christopher R., Abrahamyan, Levon G., Wood, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704627/
https://www.ncbi.nlm.nih.gov/pubmed/23861967
http://dx.doi.org/10.1371/journal.pone.0069359