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A Synthetic Model of Human Beta-Thalassemia Erythropoiesis Using CD34+ Cells from Healthy Adult Donors

Based upon the lack of clinical samples available for research in many laboratories worldwide, a significant gap exists between basic and clinical studies of beta-thalassemia major. To bridge this gap, we developed an artificially engineered model for human beta thalassemia by knocking down beta-glo...

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Detalles Bibliográficos
Autores principales: Lee, Y. Terry, Kim, Ki Soon, Byrnes, Colleen, de Vasconcellos, Jaira F., Noh, Seung-Jae, Rabel, Antoinette, Meier, Emily R., Miller, Jeffery L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704632/
https://www.ncbi.nlm.nih.gov/pubmed/23861885
http://dx.doi.org/10.1371/journal.pone.0068307