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Prediction of gene–phenotype associations in humans, mice, and plants using phenologs

BACKGROUND: Phenotypes and diseases may be related to seemingly dissimilar phenotypes in other species by means of the orthology of underlying genes. Such “orthologous phenotypes,” or “phenologs,” are examples of deep homology, and may be used to predict additional candidate disease genes. RESULTS:...

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Detalles Bibliográficos
Autores principales: Woods, John O, Singh-Blom, Ulf Martin, Laurent, Jon M, McGary, Kriston L, Marcotte, Edward M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704650/
https://www.ncbi.nlm.nih.gov/pubmed/23800157
http://dx.doi.org/10.1186/1471-2105-14-203