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Genetic variants in PARP1 (rs3219090) and IRF4 (rs12203592) genes associated with melanoma susceptibility in a Spanish population

BACKGROUND: Few high penetrance genes are known in Malignant Melanoma (MM), however, the involvement of low-penetrance genes such as MC1R, OCA2, ASIP, SLC45A2 and TYR has been observed. Lately, genome-wide association studies (GWAS) have been the ideal strategy to identify new common, low-penetrance...

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Detalles Bibliográficos
Autores principales: Peña-Chilet, Maria, Blanquer-Maceiras, Maite, Ibarrola-Villava, Maider, Martinez-Cadenas, Conrado, Martin-Gonzalez, Manuel, Gomez-Fernandez, Cristina, Mayor, Matias, Aviles, Juan Antonio, Lluch, Ana, Ribas, Gloria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704782/
https://www.ncbi.nlm.nih.gov/pubmed/23537197
http://dx.doi.org/10.1186/1471-2407-13-160