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Phosphodiesterase activity is regulated by CC2D1A that is implicated in non-syndromic intellectual disability

BACKGROUND: Cyclic adenosine 3(′),5(′)-monophosphate (cAMP) is a key regulator of many cellular processes, including in the neuronal system, and its activity is tuned by Phosphodiesterase (PDE) activation. Further, the CC2D1A protein, consisting of N-Terminal containing four DM14 domains and C-termi...

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Detalles Bibliográficos
Autores principales: Al-Tawashi, Azza, Gehring, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704924/
https://www.ncbi.nlm.nih.gov/pubmed/23826796
http://dx.doi.org/10.1186/1478-811X-11-47