Drug repositioning: a machine-learning approach through data integration

Existing computational methods for drug repositioning either rely only on the gene expression response of cell lines after treatment, or on drug-to-disease relationships, merging several information levels. However, the noisy nature of the gene expression and the scarcity of genomic data for many di...

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Detalles Bibliográficos
Autores principales: Napolitano, Francesco, Zhao, Yan, Moreira, Vânia M, Tagliaferri, Roberto, Kere, Juha, D’Amato, Mauro, Greco, Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704944/
https://www.ncbi.nlm.nih.gov/pubmed/23800010
http://dx.doi.org/10.1186/1758-2946-5-30

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704944/
https://www.ncbi.nlm.nih.gov/pubmed/23800010
http://dx.doi.org/10.1186/1758-2946-5-30

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