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Direct imaging reveals stable, micrometer-scale lipid domains that segregate proteins in live cells

It has been proposed that membrane rafts, which are sterol- and sphingolipid-enriched liquid-ordered (L(o)) domains, segregate proteins in membranes and play critical roles in numerous processes in cells. However, rafts remain controversial because they are difficult to observe in cells without inva...

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Detalles Bibliográficos
Autores principales: Toulmay, Alexandre, Prinz, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704982/
https://www.ncbi.nlm.nih.gov/pubmed/23836928
http://dx.doi.org/10.1083/jcb.201301039