Lower proportion of naïve peripheral CD8+ T cells and an unopposed pro-inflammatory response to human Cytomegalovirus proteins in vitro are associated with longer survival in very elderly people

The low percentages of naïve T cells commonly observed in elderly people are thought to be causally associated with mortality, primarily from infectious disease, and are taken as a hallmark of “immunosenescence”. Whether low levels of naive cells actually do associate with mortality has, however, no...

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Detalles Bibliográficos
Autores principales: Derhovanessian, Evelyna, Maier, Andrea B., Hähnel, Karin, Zelba, Henning, de Craen, Anton J. M., Roelofs, Helene, Slagboom, Eline P., Westendorp, Rudi G. J., Pawelec, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705124/
https://www.ncbi.nlm.nih.gov/pubmed/22661297
http://dx.doi.org/10.1007/s11357-012-9425-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705124/
https://www.ncbi.nlm.nih.gov/pubmed/22661297
http://dx.doi.org/10.1007/s11357-012-9425-7

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