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A Tale of Two Maladies? Pathogenesis of Depression with and without the Huntington’s Disease Gene Mutation

Huntington’s disease (HD) is an autosomal dominant disorder caused by a tandem repeat expansion encoding an expanded tract of glutamines in the huntingtin protein. HD is progressive and manifests as psychiatric symptoms (including depression), cognitive deficits (culminating in dementia), and motor...

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Detalles Bibliográficos
Autores principales: Du, Xin, Pang, Terence Y. C., Hannan, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705171/
https://www.ncbi.nlm.nih.gov/pubmed/23847583
http://dx.doi.org/10.3389/fneur.2013.00081