OTU Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis

Sixteen ovarian tumor (OTU) family deubiquitinases (DUBs) exist in humans, and most members regulate cell-signaling cascades. Several OTU DUBs were reported to be ubiquitin (Ub) chain linkage specific, but comprehensive analyses are missing, and the underlying mechanisms of linkage specificity are u...

Descripción completa

Detalles Bibliográficos
Autores principales: Mevissen, Tycho E.T., Hospenthal, Manuela K., Geurink, Paul P., Elliott, Paul R., Akutsu, Masato, Arnaudo, Nadia, Ekkebus, Reggy, Kulathu, Yogesh, Wauer, Tobias, El Oualid, Farid, Freund, Stefan M.V., Ovaa, Huib, Komander, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705208/
https://www.ncbi.nlm.nih.gov/pubmed/23827681
http://dx.doi.org/10.1016/j.cell.2013.05.046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705208/
https://www.ncbi.nlm.nih.gov/pubmed/23827681
http://dx.doi.org/10.1016/j.cell.2013.05.046

Ejemplares similares