Cargando…

Put a RING on it: regulation and inhibition of RNF8 and RNF168 RING finger E3 ligases at DNA damage sites

RING (Really Interesting New Gene) domain-containing E3 ubiquitin ligases comprise a large family of enzymes that in combination with an E2 ubiquitin-conjugating enzyme, modify target proteins by attaching ubiquitin moieties. A number of RING E3s play an essential role in the cellular response to DN...

Descripción completa

Detalles Bibliográficos
Autores principales: Bartocci, Cristina, Denchi, Eros Lazzerini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705210/
https://www.ncbi.nlm.nih.gov/pubmed/23847653
http://dx.doi.org/10.3389/fgene.2013.00128