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Extensive transcriptional heterogeneity revealed by isoform profiling

Transcript function is determined by sequence elements arranged on an individual RNA molecule. Variation in transcripts can affect mRNA stability, localization, and translation(2), or give rise to truncated proteins with differing subcellular localizations(3) and functions(4). Given the existence of...

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Detalles Bibliográficos
Autores principales: Pelechano, Vicent, Wei, Wu, Steinmetz, Lars M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705217/
https://www.ncbi.nlm.nih.gov/pubmed/23615609
http://dx.doi.org/10.1038/nature12121