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Extensive transcriptional heterogeneity revealed by isoform profiling
Transcript function is determined by sequence elements arranged on an individual RNA molecule. Variation in transcripts can affect mRNA stability, localization, and translation(2), or give rise to truncated proteins with differing subcellular localizations(3) and functions(4). Given the existence of...
Autores principales: | Pelechano, Vicent, Wei, Wu, Steinmetz, Lars M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705217/ https://www.ncbi.nlm.nih.gov/pubmed/23615609 http://dx.doi.org/10.1038/nature12121 |
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