P2X Receptor-Dependent Erythrocyte Damage by α-Hemolysin from Escherichia coli Triggers Phagocytosis by THP-1 Cells

The pore-forming exotoxin α-hemolysin from E. coli causes a significant volume reduction of human erythrocytes that precedes the ultimate swelling and lysis. This shrinkage results from activation of Ca(2+)-sensitive K(+) (K(Ca)3.1) and Cl(−) channels (TMEM16A) and reduced functions of either of the...

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Detalles Bibliográficos
Autores principales: Fagerberg, Steen K., Skals, Marianne, Leipziger, Jens, Praetorius, Helle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705273/
https://www.ncbi.nlm.nih.gov/pubmed/23462688
http://dx.doi.org/10.3390/toxins5030472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705273/
https://www.ncbi.nlm.nih.gov/pubmed/23462688
http://dx.doi.org/10.3390/toxins5030472

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