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Cloning and Characterization of a Hybridoma Secreting a 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-Specific Monoclonal Antibody and Recombinant F(ab)

Smokeless tobacco products have been associated with increased risks of oro-pharyngeal cancers, due in part to the presence of tobacco-specific nitrosamines (TSNAs) such as 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). These potent carcinogens are formed during tobacco curing and as a result...

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Detalles Bibliográficos
Autores principales: Wanczyk, Heather, Barker, Tolga, Rood, Debra, Zapata, Daniel I., Howell, Amy R., Richardson, Stewart K., Zinckgraf, John, Marusov, Gregory P., Lynes, Michael A., Silbart, Lawrence K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705279/
https://www.ncbi.nlm.nih.gov/pubmed/23518474
http://dx.doi.org/10.3390/toxins5030568