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Predictive Factors of Sensitivity to Elisidepsin, a Novel Kahalalide F-Derived Marine Compound

Elisidepsin (PM02734, Irvalec(®)) is a synthetic marine-derived cyclic peptide of the Kahalalide F family currently in phase II clinical development. Elisidepsin was shown to induce rapid oncosis in ErbB3-expressing cells. Other predictive factors of elisidepsin sensitivity remained unknown. A panel...

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Detalles Bibliográficos
Autores principales: Serova, Maria, de Gramont, Armand, Bieche, Ivan, Riveiro, Maria Eugenia, Galmarini, Carlos Maria, Aracil, Miguel, Jimeno, José, Faivre, Sandrine, Raymond, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705381/
https://www.ncbi.nlm.nih.gov/pubmed/23519149
http://dx.doi.org/10.3390/md11030944