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Predictive Factors of Sensitivity to Elisidepsin, a Novel Kahalalide F-Derived Marine Compound
Elisidepsin (PM02734, Irvalec(®)) is a synthetic marine-derived cyclic peptide of the Kahalalide F family currently in phase II clinical development. Elisidepsin was shown to induce rapid oncosis in ErbB3-expressing cells. Other predictive factors of elisidepsin sensitivity remained unknown. A panel...
Autores principales: | Serova, Maria, de Gramont, Armand, Bieche, Ivan, Riveiro, Maria Eugenia, Galmarini, Carlos Maria, Aracil, Miguel, Jimeno, José, Faivre, Sandrine, Raymond, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705381/ https://www.ncbi.nlm.nih.gov/pubmed/23519149 http://dx.doi.org/10.3390/md11030944 |
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