Cargando…

Astaxanthin Suppresses MPP(+)-Induced Oxidative Damage in PC12 Cells through a Sp1/NR1 Signaling Pathway

Objective: To investigate astaxanthin (ATX) neuroprotection, and its mechanism, on a 1-methyl-4-phenyl-pyridine ion (MPP(+))-induced cell model of Parkinson’s disease. Methods: Mature, differentiated PC12 cells treated with MPP(+) were used as an in vitro cell model. The MTT assay was used to invest...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ye, Qinyong, Zhang, Xiaodong, Huang, Bixia, Zhu, Yuangui, Chen, Xiaochun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705385/ https://www.ncbi.nlm.nih.gov/pubmed/23538867 http://dx.doi.org/10.3390/md11041019

Ejemplares similares

Astaxanthin protects against MPP(+)-induced oxidative stress in PC12 cells via the HO-1/NOX2 axis
por: Ye, Qinyong, et al.
Publicado: (2012)

Epigallocatechin-3-gallate suppresses 1-methyl-4-phenyl-pyridine-induced oxidative stress in PC12 cells via the SIRT1/PGC-1α signaling pathway
por: Ye, Qinyong, et al.
Publicado: (2012)

Regulation of PGC-1α mediated by acetylation and phosphorylation in MPP+ induced cell model of Parkinson’s disease
por: Fan, Fei, et al.
Publicado: (2020)

Paeonolum protects against MPP(+)-induced neurotoxicity in zebrafish and PC12 cells
por: Lu, Xi-Lin, et al.
Publicado: (2015)

Ginsenoside Rg1 and astaxanthin act on the hypothalamus to protect female mice against reproductive aging
por: Dai, Xiaoman, et al.
Publicado: (2022)

Resolvin D1 Attenuates Mpp+-Induced Parkinson Disease via Inhibiting Inflammation in PC12 Cells
por: Xu, Jinyan, et al.
Publicado: (2017)

Mitochondrial Effects of PGC-1alpha Silencing in MPP(+) Treated Human SH-SY5Y Neuroblastoma Cells
por: Ye, Qinyong, et al.
Publicado: (2017)

Overexpression of PGC-1α influences the mitochondrial unfolded protein response (mtUPR) induced by MPP(+) in human SH-SY5Y neuroblastoma cells
por: Cai, Yousheng, et al.
Publicado: (2020)

Inhibitory effects of curcumin and cyclocurcumin in 1-methyl-4-phenylpyridinium (MPP(+)) induced neurotoxicity in differentiated PC12 cells
por: Chakraborty, Sandeep, et al.
Publicado: (2017)

Astaxanthin Protects PC12 Cells against Homocysteine- and Glutamate-Induced Neurotoxicity
por: Chang, Chi-Huang, et al.
Publicado: (2020)

Efficient GSH delivery using PAMAM-GSH into MPP-induced PC12 cellular model for Parkinson’s disease
por: Sun, Hong-Ji, et al.
Publicado: (2016)

A microarray study of MPP(+)-treated PC12 Cells: Mechanisms of toxicity (MOT) analysis using bioinformatics tools
por: Xu, Zengjun, et al.
Publicado: (2005)

Inhibition of Store-Operated Calcium Entry Attenuates MPP(+)-Induced Oxidative Stress via Preservation of Mitochondrial Function in PC12 Cells: Involvement of Homer1a
por: Li, Xia, et al.
Publicado: (2013)

Protective Effects of SKF-96365, a Non-Specific Inhibitor of SOCE, against MPP(+)-Induced Cytotoxicity in PC12 Cells: Potential Role of Homer1
por: Chen, Tao, et al.
Publicado: (2013)

Early Prediction of MPP Performance: The SP2, T and Paragon Experiences
por: Xu, Z, et al.
Publicado: (1996)

Astaxanthin Inhibits p70 S6 Kinase 1 Activity to Sensitize Insulin Signaling
por: Li, Chunmei, et al.
Publicado: (2020)

Quercetin and Sesamin Protect Dopaminergic Cells from MPP(+)-Induced Neuroinflammation in a Microglial (N9)-Neuronal (PC12) Coculture System
por: Bournival, Julie, et al.
Publicado: (2012)

Upregulation of miR‐200a and miR‐204 in MPP(+)‐treated differentiated PC12 cells as a model of Parkinson’s disease
por: Talepoor Ardakani, Maryam, et al.
Publicado: (2019)

The Alteration of Nasopharyngeal and Oropharyngeal Microbiota in Children with MPP and Non-MPP
por: Lu, Zhiwei, et al.
Publicado: (2017)

Ginsenoside Rb1 Prevents MPP(+)-Induced Apoptosis in PC12 Cells by Stimulating Estrogen Receptors with Consequent Activation of ERK1/2, Akt and Inhibition of SAPK/JNK, p38 MAPK
por: Hashimoto, Ryo, et al.
Publicado: (2012)

Astaxanthin Inhibits PC-3 Xenograft Prostate Tumor Growth in Nude Mice
por: Ni, Xiaofeng, et al.
Publicado: (2017)

2013 MPP Workshop
por: Jonker, Michael
Publicado: (2014)

Illustrating and Enhancing the Biosynthesis of Astaxanthin and Docosahexaenoic Acid in Aurantiochytrium sp. SK4
por: Ye, Jingrun, et al.
Publicado: (2019)

CHIP protects against MPP(+)/MPTP-induced damage by regulating Drp1 in two models of Parkinson’s disease
por: Hu, Zhengwei, et al.
Publicado: (2021)

Characteristics of the mitochondrial and cellular uptake of MPP(+), as probed by the fluorescent mimic, 4'I-MPP(+)
por: Mapa, Mapa S. T., et al.
Publicado: (2018)

TPPU Downregulates Oxidative Stress Damage and Induces BDNF Expression in PC-12 Cells
por: Wu, Qiong, et al.
Publicado: (2022)

Streichquartett Nr. 1 ; Streichquartett Nr. 2
por: Ligeti, György, 1923-
Publicado: (1988)

Intermediates and shunt products of massiliachelin biosynthesis in Massilia sp. NR 4-1
por: Steinmetz, Till, et al.
Publicado: (2023)

Molecular characterization of direct interactions between MPP1 and flotillins
por: Biernatowska, Agnieszka, et al.
Publicado: (2021)

Spinal cord NR1 serine phosphorylation and NR2B subunit suppression following peripheral inflammation
por: Caudle, Robert M, et al.
Publicado: (2005)

NR4A1 Knockdown Suppresses Seizure Activity by Regulating Surface Expression of NR2B
por: Zhang, Yanke, et al.
Publicado: (2016)

Proceedings of the 2019 MPP Workshop
por: Strachinescu, Sabina-Ioana, et al.
Publicado: (2019)

Effects of NR1 splicing on NR1/NR3B-type excitatory glycine receptors
por: Cavara, Nora A, et al.
Publicado: (2009)

Trilobatin Protects Against Oxidative Injury in Neuronal PC12 Cells Through Regulating Mitochondrial ROS Homeostasis Mediated by AMPK/Nrf2/Sirt3 Signaling Pathway
por: Gao, Jianmei, et al.
Publicado: (2018)

Sulforaphane prevents PC12 cells from oxidative damage via the Nrf2 pathway
por: Bao, Bing, et al.
Publicado: (2019)

Effect of rutin on oxidative DNA damage in PC12 neurons cultured in nutrients deprivation condition
por: Nassiri-Asl, Marjan, et al.
Publicado: (2020)

Retracted: TPPU Downregulates Oxidative Stress Damage and Induces BDNF Expression in PC-12 Cells
por: Methods in Medicine, Computational and Mathematical
Publicado: (2023)

Corrigendum: NR4A1 Knockdown Suppresses Seizure Activity by Regulating Surface Expression of NR2B
por: Zhang, Yanke, et al.
Publicado: (2017)

Astaxanthin Ameliorates Hepatic Damage and Oxidative Stress in Carbon Tetrachloride-administered Rats
por: Islam, Md. Ariful, et al.
Publicado: (2017)

Insulin-like Growth Factor II Prevents MPP+ and Glucocorticoid Mitochondrial-Oxidative and Neuronal Damage in Dopaminergic Neurons
por: Claros, Silvia, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_oaeuri82rkiqm65sq9omvf401p