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Human Innate Immunity to Toxoplasma gondii Is Mediated by Host Caspase-1 and ASC and Parasite GRA15

Interleukin-1β (IL-1β) functions as a key regulator of inflammation and innate immunity. The protozoan parasite Toxoplasma gondii actively infects human blood monocytes and induces the production of IL-1β; however, the host and parasite factors that mediate IL-1β production during T. gondii infectio...

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Detalles Bibliográficos
Autores principales: Gov, Lanny, Karimzadeh, Alborz, Ueno, Norikiyo, Lodoen, Melissa B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705447/
https://www.ncbi.nlm.nih.gov/pubmed/23839215
http://dx.doi.org/10.1128/mBio.00255-13