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Human Innate Immunity to Toxoplasma gondii Is Mediated by Host Caspase-1 and ASC and Parasite GRA15
Interleukin-1β (IL-1β) functions as a key regulator of inflammation and innate immunity. The protozoan parasite Toxoplasma gondii actively infects human blood monocytes and induces the production of IL-1β; however, the host and parasite factors that mediate IL-1β production during T. gondii infectio...
Autores principales: | Gov, Lanny, Karimzadeh, Alborz, Ueno, Norikiyo, Lodoen, Melissa B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705447/ https://www.ncbi.nlm.nih.gov/pubmed/23839215 http://dx.doi.org/10.1128/mBio.00255-13 |
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