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X-Linked Immunodeficient Mice Exhibit Enhanced Susceptibility to Cryptococcus neoformans Infection

Bruton’s tyrosine kinase (Btk) is a signaling molecule that plays important roles in B-1 B cell development and innate myeloid cell functions and has recently been identified as a target for therapy of B cell lymphomas. We examined the contribution of B-1 B cells to resistance to Cryptococcus neofor...

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Detalles Bibliográficos
Autores principales: Szymczak, Wendy A., Davis, Michael J., Lundy, Steven K., Dufaud, Chad, Olszewski, Michal, Pirofski, Liise-anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705448/
https://www.ncbi.nlm.nih.gov/pubmed/23820392
http://dx.doi.org/10.1128/mBio.00265-13