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Reovirus Cell Entry Requires Functional Microtubules

Mammalian reovirus binds to cell-surface glycans and junctional adhesion molecule A and enters cells by receptor-mediated endocytosis in a process dependent on β1 integrin. Within the endocytic compartment, reovirus undergoes stepwise disassembly, allowing release of the transcriptionally active vir...

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Detalles Bibliográficos
Autores principales: Mainou, Bernardo A., Zamora, Paula F., Ashbrook, Alison W., Dorset, Daniel C., Kim, Kwang S., Dermody, Terence S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705452/
https://www.ncbi.nlm.nih.gov/pubmed/23820395
http://dx.doi.org/10.1128/mBio.00405-13