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Reovirus Cell Entry Requires Functional Microtubules
Mammalian reovirus binds to cell-surface glycans and junctional adhesion molecule A and enters cells by receptor-mediated endocytosis in a process dependent on β1 integrin. Within the endocytic compartment, reovirus undergoes stepwise disassembly, allowing release of the transcriptionally active vir...
Autores principales: | Mainou, Bernardo A., Zamora, Paula F., Ashbrook, Alison W., Dorset, Daniel C., Kim, Kwang S., Dermody, Terence S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705452/ https://www.ncbi.nlm.nih.gov/pubmed/23820395 http://dx.doi.org/10.1128/mBio.00405-13 |
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