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Effects of poly (ADP-ribosyl) polymerase (PARP) inhibitor on cisplatin resistance & proliferation of the ovarian cancer C13(*) cells

BACKGROUND & OBJECTIVES: Drug resistance is the primary cause of failure in the treatment of cancers. It has been suggested that the enhancement of DNA repair capability may be responsible for the drug resistance of the tumour cells, and poly(ADP-ribosyl)ation plays an important role in DNA repa...

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Detalles Bibliográficos
Autores principales: Zhang, Jingjing, Kan, Yanyan, Tian, Yongjie, Wang, Zhe, Zhang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705661/
https://www.ncbi.nlm.nih.gov/pubmed/23640560