Susceptibility for Lupus Nephritis by Low Copy Number of the FCGR3B Gene Is Linked to Increased Levels of Pathogenic Autoantibodies

Low copy number (CN) of the FCGR3B gene reduces FCGR3B membrane expression on neutrophils and results in clearance of a smaller amount of immune complex. We investigated FCGR3B CN in relation to the clinical phenotype in a Caucasian SLE cohort (n = 107). FCGR3B CN was determined by three different q...

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Detalles Bibliográficos
Autores principales: Nossent, Johannes C., Becker-Merok, Andrea, Rischmueller, Maureen, Lester, Sue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705838/
https://www.ncbi.nlm.nih.gov/pubmed/23864940
http://dx.doi.org/10.1155/2013/750814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705838/
https://www.ncbi.nlm.nih.gov/pubmed/23864940
http://dx.doi.org/10.1155/2013/750814

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