Posttranslational Nitration of Tyrosine Residues Modulates Glutamate Transmission and Contributes to N-Methyl-D-aspartate-Mediated Thermal Hyperalgesia

Activation of the N-methyl-D-aspartate receptor (NMDAR) is fundamental in the development of hyperalgesia. Overactivation of this receptor releases superoxide and nitric oxide that, in turn, forms peroxynitrite (PN). All of these events have been linked to neurotoxicity. The receptors and enzymes in...

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Detalles Bibliográficos
Autores principales: Muscoli, Carolina, Dagostino, Concetta, Ilari, Sara, Lauro, Filomena, Gliozzi, Micaela, Bardhi, Erlisa, Palma, Ernesto, Mollace, Vincenzo, Salvemini, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705874/
https://www.ncbi.nlm.nih.gov/pubmed/23864769
http://dx.doi.org/10.1155/2013/950947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705874/
https://www.ncbi.nlm.nih.gov/pubmed/23864769
http://dx.doi.org/10.1155/2013/950947

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