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Disruption of the blood–brain barrier after generalized tonic-clonic seizures correlates with cerebrospinal fluid MMP-9 levels

BACKGROUND: Increasing evidence suggests seizures cause blood–brain barrier (BBB) dysfunction including decreased seizure threshold and higher onset potential of future seizures. However, the mechanisms underlying BBB damage in seizures remains poorly understood. Evidence in human and animal models...

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Detalles Bibliográficos
Autores principales: Li, Ya-Jun, Wang, Zheng-Hai, Zhang, Bei, Zhe, Xiao, Wang, Ming-Jue, Shi, Shao-Ting, Bai, Jing, Lin, Tao, Guo, Chang-Jiang, Zhang, Shi-Jun, Kong, Xiang-Li, Zuo, Xing, Zhao, Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706217/
https://www.ncbi.nlm.nih.gov/pubmed/23829879
http://dx.doi.org/10.1186/1742-2094-10-80