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Bcr-Abl tyrosine kinase inhibitors- current status

Bcr-Abl plays a central role in the development of chromosome positive leukaemia. Chronic Myeloid leukaemia occurs due to increase proliferation and resistance to apoptosis by Bcr-Abl positive cells. Imatinib (STI571) is the first drug in the family of Bcr-Abl tyrosine kinase inhibitors while Niloti...

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Detalles Bibliográficos
Autores principales: Mughal, Anum, Aslam, Hafiz Muhammad, Khan, Aga Muhammad Hammad, Saleem, Shafaq, Umah, Ribak, Saleem, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706229/
https://www.ncbi.nlm.nih.gov/pubmed/23787070
http://dx.doi.org/10.1186/1750-9378-8-23