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Cubilin expression is monoallelic and epigenetically augmented via PPARs

BACKGROUND: Cubilin is an endocytic receptor that is necessary for renal and intestinal absorption of a range of ligands. Endocytosis mediated by cubilin and its co-receptor megalin is the principal mechanism for proximal tubule reabsorption of proteins from the glomerular filtrate. Cubilin is also...

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Detalles Bibliográficos
Autores principales: Aseem, Obaidullah, Barth, Jeremy L, Klatt, Sandra C, Smith, Brian T, Argraves, W Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706236/
https://www.ncbi.nlm.nih.gov/pubmed/23773363
http://dx.doi.org/10.1186/1471-2164-14-405