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Using ancestral information to detect and localize quantitative trait loci in genome-wide association studies

BACKGROUND: In mammalian genetics, many quantitative traits, such as blood pressure, are thought to be influenced by specific genes, but are also affected by environmental factors, making the associated genes difficult to identify and locate from genetic data alone. In particular, the application of...

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Detalles Bibliográficos
Autores principales: Thompson, Katherine L, Kubatko, Laura S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706278/
https://www.ncbi.nlm.nih.gov/pubmed/23786262
http://dx.doi.org/10.1186/1471-2105-14-200