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Conditionally-live attenuated SIV upregulates global T effector memory cell frequency under replication permissive conditions

BACKGROUND: Live attenuated SIV induces potent protection against superinfection with virulent virus; however the mechanism of this vaccine effect is poorly understood. Such knowledge is important for the development of clinically acceptable vaccine modalities against HIV. RESULTS: Using a novel, do...

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Detalles Bibliográficos
Autores principales: Manoussaka, Maria S, Berry, Neil, Ferguson, Deborah, Stebbings, Richard, Robinson, Mark, Ham, Claire, Page, Mark, Li, Bo, Das, Atze T, Berkhout, Ben, Almond, Neil, Cranage, Martin P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706341/
https://www.ncbi.nlm.nih.gov/pubmed/23738926
http://dx.doi.org/10.1186/1742-4690-10-59