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Combination Therapy of VEGF-Trap and Gemcitabine Results in Improved Anti-Tumor Efficacy in a Mouse Lung Cancer Model

BACKGROUND: Angiogenesis is essential for the growth and metastasis of cancer. Although anti-angiogenic agents, particularly vascular endothelial growth factor (VEGF) inhibitors, have exhibited single-agent activity, there is considerable interest in combining these novel drugs with conventional che...

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Detalles Bibliográficos
Autores principales: Zhou, Shuang, Yang, Yang, Yang, Yaoqin, Tao, Huihong, Li, Dong, Zhang, Junli, Jiang, Gening, Fang, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706404/
https://www.ncbi.nlm.nih.gov/pubmed/23874680
http://dx.doi.org/10.1371/journal.pone.0068589