High Cytoplasmic FOXO1 and pFOXO1 Expression in Astrocytomas Are Associated with Worse Surgical Outcome

FOXO1 is at a convergence point of receptor tyrosine kinase (RTK) signaling, which is one of the three core pathways implicated in glioblastoma. It was recently shown that FOXO1 can effectively induce glioma cell death and inhibit tumor growth through cell cycle arrest and apoptosis. We therefore ev...

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Detalles Bibliográficos
Autores principales: Chen, Chao, Xu, Tao, Zhou, Jinxu, Yan, Yong, Li, Weiqing, Yu, Hongyu, Hu, Guohan, Ding, Xuehua, Chen, Juxiang, Lu, Yicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706417/
https://www.ncbi.nlm.nih.gov/pubmed/23874926
http://dx.doi.org/10.1371/journal.pone.0069260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706417/
https://www.ncbi.nlm.nih.gov/pubmed/23874926
http://dx.doi.org/10.1371/journal.pone.0069260

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