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High Cytoplasmic FOXO1 and pFOXO1 Expression in Astrocytomas Are Associated with Worse Surgical Outcome
FOXO1 is at a convergence point of receptor tyrosine kinase (RTK) signaling, which is one of the three core pathways implicated in glioblastoma. It was recently shown that FOXO1 can effectively induce glioma cell death and inhibit tumor growth through cell cycle arrest and apoptosis. We therefore ev...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706417/ https://www.ncbi.nlm.nih.gov/pubmed/23874926 http://dx.doi.org/10.1371/journal.pone.0069260 |