Cargando…

Partially Silencing Brain Toll-Like Receptor 4 Prevents in Part Left Ventricular Remodeling with Sympathoinhibition in Rats with Myocardial Infarction-Induced Heart Failure

BACKGROUND: Left ventricular (LV) remodeling and activation of sympathetic nervous system (SNS) are cardinal features of heart failure. We previously demonstrated that enhanced central sympathetic outflow is associated with brain toll-like receptor 4 (TLR4) probably mediated by brain angiotensin II...

Descripción completa

Detalles Bibliográficos
Autores principales: Ogawa, Kiyohiro, Hirooka, Yoshitaka, Kishi, Takuya, Ide, Tomomi, Sunagawa, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706428/
https://www.ncbi.nlm.nih.gov/pubmed/23874864
http://dx.doi.org/10.1371/journal.pone.0069053