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Partially Silencing Brain Toll-Like Receptor 4 Prevents in Part Left Ventricular Remodeling with Sympathoinhibition in Rats with Myocardial Infarction-Induced Heart Failure
BACKGROUND: Left ventricular (LV) remodeling and activation of sympathetic nervous system (SNS) are cardinal features of heart failure. We previously demonstrated that enhanced central sympathetic outflow is associated with brain toll-like receptor 4 (TLR4) probably mediated by brain angiotensin II...
Autores principales: | Ogawa, Kiyohiro, Hirooka, Yoshitaka, Kishi, Takuya, Ide, Tomomi, Sunagawa, Kenji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706428/ https://www.ncbi.nlm.nih.gov/pubmed/23874864 http://dx.doi.org/10.1371/journal.pone.0069053 |
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