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Dry-Coated Live Viral Vector Vaccines Delivered by Nanopatch Microprojections Retain Long-Term Thermostability and Induce Transgene-Specific T Cell Responses in Mice

The disadvantages of needle-based immunisation motivate the development of simple, low cost, needle-free alternatives. Vaccine delivery to cutaneous environments rich in specialised antigen-presenting cells using microprojection patches has practical and immunological advantages over conventional ne...

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Detalles Bibliográficos
Autores principales: Pearson, Frances E., McNeilly, Celia L., Crichton, Michael L., Primiero, Clare A., Yukiko, Sally R., Fernando, Germain J. P., Chen, Xianfeng, Gilbert, Sarah C., Hill, Adrian V. S., Kendall, Mark A. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706440/
https://www.ncbi.nlm.nih.gov/pubmed/23874462
http://dx.doi.org/10.1371/journal.pone.0067888