Cargando…

Dry-Coated Live Viral Vector Vaccines Delivered by Nanopatch Microprojections Retain Long-Term Thermostability and Induce Transgene-Specific T Cell Responses in Mice

The disadvantages of needle-based immunisation motivate the development of simple, low cost, needle-free alternatives. Vaccine delivery to cutaneous environments rich in specialised antigen-presenting cells using microprojection patches has practical and immunological advantages over conventional ne...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pearson, Frances E., McNeilly, Celia L., Crichton, Michael L., Primiero, Clare A., Yukiko, Sally R., Fernando, Germain J. P., Chen, Xianfeng, Gilbert, Sarah C., Hill, Adrian V. S., Kendall, Mark A. F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706440/ https://www.ncbi.nlm.nih.gov/pubmed/23874462 http://dx.doi.org/10.1371/journal.pone.0067888

Ejemplares similares

Development of Stabilizing Formulations of a Trivalent Inactivated Poliovirus Vaccine in a Dried State for Delivery in the Nanopatch™ Microprojection Array
por: Wan, Ying, et al.
Publicado: (2018)

Inactivated poliovirus type 2 vaccine delivered to rat skin via high density microprojection array elicits potent neutralising antibody responses
por: Muller, David A., et al.
Publicado: (2016)

Microprojection with X-rays
por: Poen, Ong Sing
Publicado: (1959)

Potent response of QS-21 as a vaccine adjuvant in the skin when delivered with the Nanopatch, resulted in adjuvant dose sparing
por: Ng, Hwee-Ing, et al.
Publicado: (2016)

Efficient Delivery of Dengue Virus Subunit Vaccines to the Skin by Microprojection Arrays
por: Muller, David A., et al.
Publicado: (2019)

Superior efficacy of a skin-applied microprojection device for delivering a novel Zika DNA vaccine
por: Wijesundara, Danushka K., et al.
Publicado: (2023)

Immune response and reactogenicity of an unadjuvanted intradermally delivered human papillomavirus vaccine using a first generation Nanopatch™ in rhesus macaques: An exploratory, pre-clinical feasibility assessment
por: Meyer, Brian K., et al.
Publicado: (2019)

Microneedles and Nanopatches-Based Delivery Devices in Dentistry
por: Batra, Panchali, et al.
Publicado: (2020)

Plasmonic nanopatch array for optical integrated circuit applications
por: Qu, Shi-Wei, et al.
Publicado: (2013)

Optically pumped subwavelength-scale metallodielectric nanopatch resonators
por: Kwon, Kyungmok, et al.
Publicado: (2016)

Colloidal Synthesis of Nanopatch Antennas for Applications in Plasmonics and Nanophotonics
por: Hoang, Thang B., et al.
Publicado: (2016)

Microprojection arrays applied to skin generate mechanical stress, induce an inflammatory transcriptome and cell death, and improve vaccine-induced immune responses
por: Ng, Hwee-Ing, et al.
Publicado: (2019)

Biologically Targeted Photo‐Crosslinkable Nanopatch to Prevent Postsurgical Peritoneal Adhesion
por: Mi, Yu, et al.
Publicado: (2019)

Mode-Matching Enhancement of Second-Harmonic Generation with Plasmonic Nanopatch Antennas
por: Noor, Ahsan, et al.
Publicado: (2020)

High-density microprojection array delivery to rat skin of low doses of trivalent inactivated poliovirus vaccine elicits potent neutralising antibody responses
por: Muller, David A., et al.
Publicado: (2017)

A 3D-printed transepidermal microprojection array for human skin microbiome sampling
por: Liang, Kun, et al.
Publicado: (2022)

Electronic Structure and Luminescence of Quasi-Freestanding MoS(2) Nanopatches on Au(111)
por: Krane, Nils, et al.
Publicado: (2016)

Formulation Development and Improved Stability of a Combination Measles and Rubella Live-Viral Vaccine Dried for Use in the Nanopatch(TM) Microneedle Delivery System
por: Wan, Ying, et al.
Publicado: (2021)

Cutting efficiency of apical preparation using ultrasonic tips with microprojections: confocal laser scanning microscopy study
por: Kwak, Sang-Won, et al.
Publicado: (2014)

Enhanced generation and anisotropic Coulomb scattering of hot electrons in an ultra-broadband plasmonic nanopatch metasurface
por: Sykes, Matthew E., et al.
Publicado: (2017)

Recruitment, Retainment, and Biomarkers of Response; A Pilot Trial of Lithium in Humans With Mild Cognitive Impairment
por: Duthie, Ashleigh, et al.
Publicado: (2019)

Publisher Correction: Enhanced generation and anisotropic Coulomb scattering of hot electrons in an ultra-broadband plasmonic nanopatch metasurface
por: Sykes, Matthew E., et al.
Publicado: (2017)

Nanomedicine: Biologically Targeted Photo‐Crosslinkable Nanopatch to Prevent Postsurgical Peritoneal Adhesion (Adv. Sci. 19/2019)
por: Mi, Yu, et al.
Publicado: (2019)

Horizontal gene transfer and recombination in Streptococcus dysgalactiae subsp. equisimilis
por: McNeilly, Celia L., et al.
Publicado: (2014)

Co-localization of cell death with antigen deposition in skin enhances vaccine immunogenicity
por: Depelsenaire, Alexandra C.I., et al.
Publicado: (2014)

Sun Tzu y el arte de los negocios : seis estrategias fundamentales para el hombre de negocios
por: McNeilly, Mark
Publicado: (1999)

Faecal Microbiota Transplantation for Clostridium Difficile – a local perspective
por: Diamond, C, et al.
Publicado: (2017)

Transgenic soybean expressing a thermostable phytase as substitution for feed additive phytase
por: Zhao, Yu, et al.
Publicado: (2019)

Towards the Immunoproteome of Neisseria meningitidis
por: Mendum, Tom A., et al.
Publicado: (2009)

Bone morphogenetic protein-4 interacts with activin and GnRH to modulate gonadotrophin secretion in LβT2 gonadotrophs
por: Nicol, L, et al.
Publicado: (2008)

Transcutaneous delivery and thermostability of a dry trivalent inactivated influenza vaccine patch
por: Frolov, Vladimir G., et al.
Publicado: (2008)

Inhibin removes the inhibitory effects of activin on steroid enzyme expression and androgen production by normal ovarian thecal cells
por: Young, J M, et al.
Publicado: (2012)

Effect of Chemical Stabilizers on the Thermostability and Infectivity of a Representative Panel of Freeze Dried Viruses
por: Pastorino, Boris, et al.
Publicado: (2015)

A Thermostable β-Glucuronidase Obtained by Directed Evolution as a Reporter Gene in Transgenic Plants
por: Xiong, Ai-Sheng, et al.
Publicado: (2011)

Trends in Thermostability Provide Information on the Nature of Substrate, Inhibitor, and Lipid Interactions with Mitochondrial Carriers
por: Crichton, Paul G., et al.
Publicado: (2015)

Immune modulation by helminth parasites of ruminants: implications for vaccine development and host immune competence
por: McNeilly, Tom N., et al.
Publicado: (2014)

Not Feeling Swell: Superior Vena Cava (SVC) Syndrome Falsely Attributed to COVID-19 Vaccine Reaction
por: McNeilly, Bryan P., et al.
Publicado: (2022)

Solid Bioneedle-Delivered Influenza Vaccines Are Highly Thermostable and Induce Both Humoral and Cellular Immune Responses
por: Soema, Peter C., et al.
Publicado: (2014)

Thermostable Proteins
por: Sen, Srikanta, et al.
Publicado: (2016)

Patient and carer experience of obtaining regular prescribed medication for chronic disease in the English National Health Service: a qualitative study
por: Wilson, Patricia M, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_0r3rnbt2uh03a8mf9v45uf7fis