The Asymmetric Binding of PGC-1α to the ERRα and ERRγ Nuclear Receptor Homodimers Involves a Similar Recognition Mechanism

BACKGROUND: PGC-1α is a crucial regulator of cellular metabolism and energy homeostasis that functionally acts together with the estrogen-related receptors (ERRα and ERRγ) in the regulation of mitochondrial and metabolic gene networks. Dimerization of the ERRs is a pre-requisite for interactions wit...

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Detalles Bibliográficos
Autores principales: Takacs, Maria, Petoukhov, Maxim V., Atkinson, R. Andrew, Roblin, Pierre, Ogi, François-Xavier, Demeler, Borries, Potier, Noelle, Chebaro, Yassmine, Dejaegere, Annick, Svergun, Dmitri I., Moras, Dino, Billas, Isabelle M. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706463/
https://www.ncbi.nlm.nih.gov/pubmed/23874451
http://dx.doi.org/10.1371/journal.pone.0067810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706463/
https://www.ncbi.nlm.nih.gov/pubmed/23874451
http://dx.doi.org/10.1371/journal.pone.0067810

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