Insulin Receptor-Overexpressing β-Cells Ameliorate Hyperglycemia in Diabetic Rats through Wnt Signaling Activation

To investigate the therapeutic efficacy and mechanism of β-cells with insulin receptor (IR) overexpression on diabetes mellitus (DM), rat insulinoma (INS-1) cells were engineered to stably express human insulin receptor (INS-IR cells), and subsequently transplanted into streptozotocin- induced diabe...

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Detalles Bibliográficos
Autores principales: Kim, Mi-Hyun, Hong, Seung-Hyun, Lee, Moon-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706479/
https://www.ncbi.nlm.nih.gov/pubmed/23874448
http://dx.doi.org/10.1371/journal.pone.0067802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706479/
https://www.ncbi.nlm.nih.gov/pubmed/23874448
http://dx.doi.org/10.1371/journal.pone.0067802

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