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A Novel, Non-canonical Splice Variant of the Ikaros Gene Is Aberrantly Expressed in B-cell Lymphoproliferative Disorders

The Ikaros gene encodes a Krüppel-like zinc-finger transcription factor involved in hematopoiesis regulation. Ikaros has been established as one of the most clinically relevant tumor suppressors in several hematological malignancies. In fact, expression of dominant negative Ikaros isoforms is associ...

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Detalles Bibliográficos
Autores principales: Capece, Daria, Zazzeroni, Francesca, Mancarelli, Maria Michela, Verzella, Daniela, Fischietti, Mariafausta, Di Tommaso, Ambra, Maccarone, Rita, Plebani, Sara, Di Ianni, Mauro, Gulino, Alberto, Alesse, Edoardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706598/
https://www.ncbi.nlm.nih.gov/pubmed/23874502
http://dx.doi.org/10.1371/journal.pone.0068080