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Headcase Promotes Cell Survival and Niche Maintenance in the Drosophila Testis

At the apical tip of the Drosophila testis, germline and somatic stem cells surround a cluster of somatic cells called the hub. Hub cells produce a self-renewal factor, Unpaired (Upd), that activates the JAK-STAT pathway in adjacent stem cells to regulate stem cell behavior. Therefore, apical hub ce...

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Detalles Bibliográficos
Autores principales: Resende, Luís Pedro F., Boyle, Monica, Tran, Darrell, Fellner, Thomas, Jones, D. Leanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706621/
https://www.ncbi.nlm.nih.gov/pubmed/23874487
http://dx.doi.org/10.1371/journal.pone.0068026