Role of Urokinase Receptor in Tumor Progression and Development

Elevated level of urokinase receptor (uPAR) is detected in various aggressive cancer types and is closely associated with poor prognosis of cancers. Binding of uPA to uPAR triggers the conversion of plasminogen to plasmin and the subsequent activation of metalloproteinases. These events confer tumor...

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Detalles Bibliográficos
Autores principales: Noh, Hyangsoon, Hong, Sungguan, Huang, Shuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706692/
https://www.ncbi.nlm.nih.gov/pubmed/23843896
http://dx.doi.org/10.7150/thno.4218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706692/
https://www.ncbi.nlm.nih.gov/pubmed/23843896
http://dx.doi.org/10.7150/thno.4218

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