Isoform level expression profiles provide better cancer signatures than gene level expression profiles

BACKGROUND: The majority of mammalian genes generate multiple transcript variants and protein isoforms through alternative transcription and/or alternative splicing, and the dynamic changes at the transcript/isoform level between non-oncogenic and cancer cells remain largely unexplored. We hypothesi...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, ZhongFa, Pal, Sharmistha, Bi, Yingtao, Tchou, Julia, Davuluri, Ramana V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706752/
https://www.ncbi.nlm.nih.gov/pubmed/23594586
http://dx.doi.org/10.1186/gm437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706752/
https://www.ncbi.nlm.nih.gov/pubmed/23594586
http://dx.doi.org/10.1186/gm437

Ejemplares similares