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Comprehensive behavioral characterization of an APP/PS-1 double knock-in mouse model of Alzheimer's disease
INTRODUCTION: Despite the extensive mechanistic and pathological characterization of the amyloid precursor protein (APP)/presenilin-1 (PS-1) knock-in mouse model of Alzheimer's disease (AD), very little is known about the AD-relevant behavioral deficits in this model. Characterization of the ba...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706792/ https://www.ncbi.nlm.nih.gov/pubmed/23705774 http://dx.doi.org/10.1186/alzrt182 |